Helicobacter pylori, referred to as HP (Helicobocton Pyloni), is Gram-negative, with arc-shaped, S-shaped or spiral-shaped bacteria, flagella, and active movement. It is a spiral, slightly anaerobic bacterium that has very demanding growth conditions. It lives in various areas of the stomach and duodenum, causing mild chronic inflammation of the gastric mucosa, leading to gastric and duodenal ulcers and gastric cancer. It is the only known microbial species that can survive in the human stomach and is classified as a Class 1 carcinogen by the World Health Organization's International Agency for Research on Cancer.
Commonly used detection methods for Helicobacter pylori
Breath test
Breath tests include C-13 and C-14 breath tests. Both are methods of diagnosing diseases by collecting the components of the patient's exhaled gas and analyzing the differences between them and the components of the exhaled gas of normal people.
✅Advantages: non-invasive and highly accurate.
❌Disadvantages: susceptible to drug interference, C-14 is not suitable for children and pregnant women.
Serological testing
Blood tests are done, but a positive result can only indicate that the infection has occurred recently or is currently ongoing, and it is difficult to evaluate the eradication effect.
✅Advantages: convenient, most suitable for epidemiological surveys.
❌Disadvantages: Requires blood draw; cannot be used as a test for current Helicobacter pylori infection.
Gastroscopy
While doing the gastroscopy, 1-2 pieces of gastric tissue are taken for examination, mainly including rapid urease test, histological examination and Helicobacter pylori culture.
✅Advantage:High accuracy of test results
❌Shortcoming:It is traumatic and may cause nausea, vomiting, pain and other discomforts to the subject.
Colloidal gold detection method
The subjects only need to collect stool samples without taking any reagents orally. It is suitable for patients of all ages (including children and the elderly) and all types (including pregnant women) and has no toxic reactions. Since the test is for Hp antigen, it can accurately reflect the Hp infection situation, and a positive result can be identified as Hp infection.
✅Advantage:The method is simple, anyone is not restricted and it is highly safe.
❌Shortcoming:Keep the feces.
The upgraded version of Helicobacter pylori detection raw materials launched by East-Mab Bio Biological has greatly improved performance!
High sensitivity,Detectable50pg/mL antigen。
Good specificity, no crosstalk and interference
Rapid response, results in 10 minutes
Platform Information Submission-Privacy Agreement
· Privacy Policy
No content yet
Platform Information Statement-Laws and Regulations
· Laws and regulations
Trademark registration of Jiangsu Dongkang Biomedical Technology Co., Ltd.
East Mab
East Mab Bio
东抗生物