Y02801 Recombinant Human IL-18 Product Brochure

Cat#:Y02801

Name:Y02801 Recombinant Human IL-18

Species:Human

Specification:10μg/50μg/1mg

Purity:≥95%

Endotoxin: ≤10 EU/mg

Expression System:CHO

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Product Details

Cat. No.

Y02801

Purity

≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining)

Endotoxin

≤10 EU/mg by the LAL method

Bioactivity

Measured by its ability to induce IFN-gamma secretion by KG‑1 human acute myelogenous leukemia cells in the presence of TNF-alpha. The ED₅₀ for this effect is ≤2.0 ng/mL.

Accession

Q14116

Alternative Names

Interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma;GIF; IL-18; IL-1g; IL1F4; MG/VAIL C12320

Species

Human

Expression System

CHO

Target Protein Sequence

YFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTVQNED

Mol. Weight

18.2 kDa

Expression Region

Tyr37-Asp193

Tag Info

Tag free

Formulation

Lyophilized

Buffer

PBS,5% mannitol and 0.01% Tween 80, pH7.4

Size

10μg/vail 50μg/vail 1mg/vail

Lead Time

Products are in stock,but custom products may require further consultation

Reconstitution

It is recommended to redissolve in sterile deionized water.

Shipping

The product is shipped with blue ice

Storage & Stability

36 months at 2°C to 8°C in lyophilized state

6 months at -20°C to -80°C under sterile conditions after reconstitution

7-10 days at 2°C to 8°C under sterile conditions after reconstitution

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Data

Bioactivity

Measured by its ability to induce IFN-gamma secrection by KG-1 cells in the presence of TNF-alpha. The ED₅₀ for this effect is ≤2.0 ng/mL. The Bioactivity of Recombinant Human IL-18 (Cat. No. Y02801) is equivalent to other competing products.