Cat#:Y03301
Name:Y03301 Recombinant Human Noggin
Species:Human
Specification:10μg/50μg/1mg
Purity:≥95%
Endotoxin: ≤10 EU/mg
Expression System:CHO
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Y03301 Recombinant Human Noggin
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Product Details Cat. No.
Y03301
Purity
≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining)
Endotoxin
≤10 EU/mg by the LAL method
Bioactivity
Derermined by its abitity to inhibit 5.0 ng/ml of BMP-4 induced alkaline phosphatase production by ATDC-5 chondrogenic cells. The ED50 for this effect is 2.0-3.0 ng/mL of Noggin.
Accession
Q13253
Alternative Names
Noggin; NOG
Species
Human
Expression System
CHO
Target Protein Sequence
QHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATSPPEDRPGGGGGAAGGAEDLAELDQLLRQRPSGAMPSEIKGLEFSEGLAQGKKQRLSKKLRRKLQMWLWSQTFCPVLYAWNDLGSRFWPRYVKVGSCFSKRSCSVPEGMVCKPSKSVHLTVLRWRCQRRGGQRCGWIPIQYPIISECKCSC
Mol. Weight
23 kDa
Expression Region
Gln28-Cys232
Tag Info
Tag free
Formulation
Lyophilized
Buffer
PBS,5% mannitol and 0.01% Tween 80, pH7.4
Size
10μg/vail 50μg/vail 1mg/vail
Lead Time
Products are in stock,but custom products may require further consultation
Reconstitution
It is recommended to redissolve in sterile deionized water.
Shipping
The product is shipped with blue ice
Storage & Stability
36 months at 2°C to 8°C in lyophilized state
6 months at -20°C to -80°C under sterile conditions after reconstitution
7-10 days at 2°C to 8°C under sterile conditions after reconstitution
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
SDS-PAGE
Recombinant Human Noggin (Cat. No. Y03301) SDS-PAGE under reducing (R) & Non-reducing conditions. The gel was stained with Y03301 SDS-PAGE.
Bioactivity
Measured by its ability to inhibit 5.0 ng/mlof BMP-4 induced alkaline phosphatase production by ATDC-5 chondrocenic cells. The Bioactivity of Recombinant Human Noggin （Cat No.Y03301） is equivalent to competitor.
Bioactivity
Highly consistent bioactivity between different production batches of Recombinant Human Noggin (Cat. No. Y03301).
Jiangsu East-Mab Bio：Building 13 and 17, 888 Zhujiang Road, Nantong, Jiangsu 226499 , China
Suzhou East-Mab Bio：Floor 5 & 6, Building 1, 168 Majian Road, Suzhou, Jiangsu 215129, China
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